Histology of a plaque showed an exclusive folliculotropism of atypical lymphocytes sometimes forming follicular pautriers microabscesses, and the lack of epidermotropism and follicular mucinosis. Folliculotropic mycosis fungoides annals of clinical case reports. Follicular mucinosis is a disease characterized by follicular degeneration and mucin accumulation. Follicular mucinosis definition of follicular mucinosis. It may be primary idiopathic or secondary to mycosis fungoides or reticulosis. Updated classification of papular mucinosis, lichen.
Follicular mucinosis is a dermatosis characterized by mucin depot in the skin, the follicular. Histology, ces, test 4, bloo learn with flashcards, games, and more for free. Follicular mucinosis has, clinically, keratotic follicular papules specially distributed in the scalp and face, affecting the neck, trunk and extremities. A disease of the pilosebaceous unit, presenting clinically as grouped follicular papules or plaques with associated hair loss. If you continue browsing the site, you agree to the use of cookies on this website. It includes cases with and without follicular mucinosis material and method. Histologia del periodonto by xavier padilla diaz on prezi. Pdf follicular mucinosis, also known as alopecia mucinosa, is a cutaneous mucinosis histologically characterized by accumulation of dermal. Sebaceoma, as a term, is used for tumors with 50% basaloid cells and sebaceous adenoma is used for tumors with may 29, 2019 please use one of the following formats to cite this article in your essay, paper or report. It can be seen in mycosis fungoides, although idiopathic or forms associated with other diseases are also known. Follicular mucinosis fm is a cutaneous mucinosis in which mucinosis folicular is a buildup of mucin at the external root sheath and with much less frequency in the sebaceous gland. Perelman department of dermatology, new york university abstract.
The localised form presents with firm, waxy papules with localised distribution and without systemic features. Citologia glandulas salivales severino rey nodar, md, phd 2. Sebaceoma, as a term, is used for tumors with 50% basaloid cells and sebaceous adenoma is used for tumors with follicular mucinosis a disease of the pilosebaceous unit, presenting clinically as grouped follicular papules or plaques with associated hair loss, caused by mucinous infiltration of tissues, and usually involving the scalp, face, and neck. This paper reports the case of a 60yearold man with a dermatosis of 4 months, with the appearance of follicular papules on the. Follicular mucinosis is a dermatosis characterized by mucin depot in the skin, the follicular and sebaceous epithelium, which has been associated with lymphoproliferative disorders such as mycosis fungoides. Follicular mucinosis presenting as an acneiform eruption. Fm presents as erythematous, slightly scaling patches, plaques and nodules or. Follicular mucinosis was first reported by pinkus3 in 1957 in a description of the histology findings for a series of patients with characteristic cutaneous lesions. Histology of a plaque showed an exclusive folliculotropism of atypical lymphocytes sometimes forming follicular pautrier. Follicular mucinosis associated with mycosis fungoides lesley clarkloeser md, and joann latkowski md dermatology online journal 10 3.
This is a hair loss condition that can occur at any age. A 62yearold man with a year history of mycosis fungoides presented with a 2month history of alopecia of the scalp. It is believed that follicular keratinocytes are responsible for mucin production, as a response to the stimulus of cytokines released by perifollicular t lymphocytes. The generalised form also known as scleromyxoedema presents with widespread fleshcoloured papules arranged in lines and progressive skin thickening. Oral focal mucinosis is the microscopic counterpart of the cutaneous focal mucinosis or cutaneous myxoid cyst. Oct 18, 2012 histologia tema 23 del profesor carlos mendoza slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Dermis follicular mucinosis information on the diagnosis. Matriz extracelular tecido celulas matriz extracelular tecido epitelial poliedricas e justapostas pequena quantidade tecido conjuntivo fixas e migratorias abundante tecido muscular alongadas e contrateis quantidade moderada tecido nervoso com longos prolongamentos nenhuma prof. Micosis fungoide folicular cutanea y ganglionar sciencedirect. Dermis sindrome rem o mucinosis reticular eritematosa. Follicular mucinosis and follicular mycosis fungoides. Micosis fungoide folicular cutanea y ganglionar actas dermo.
Follicular mucinosis is a disorder histopathologically defined by the accumulation of mucin in hair follicles and sebaceous glands, which undergo epithelial reticular degeneration. Hiromasa nikai, in diagnostic surgical pathology of the head and neck second edition, 2009. Follicular mucinosis is an uncommon inflammatory disorder that characteristically presents as follicular papules andor indurated plaques. Pdf descripcion histologica del complejo folicular piloso. May 29, 2019 please use one of the following formats to cite this article in your essay, paper or report.
Lichen myxoedematosus or papular mucinosis is a rare skin disorder characterised by mucin deposits in the skin. Last, we propose a concept, and a terminology that derives from it, that synthesizes all that is known now about alopecia mucinosa and follicular mucinosis, in particular the relationship of alopecia mucinosa to mycosis fungoides, including follicular, syringotropic, and erythrodermic manifestations of it. Longterm followup of patients younger than 40 years with and without clonal tcell receptor gene rearrangement. It may be primary idiopathic, occurring most often in children, or it may be secondary to mycosis fungoides or reticulosis. We report the retrospective analysis of clinical, histopathological, and immunohistochemical aspects, therapeutic responses and followup of six cases of folliculotropic mycosis fungoides studied in the department of dermatology from may 1994 to june 2010. It is caused by mucinous infiltration of tissues, and usually involving the scalp, face, and neck. Follicular mucinosis associated with mycosis fungoides. Histology shows medium to large atypical tcells with cerebriform nuclei. Follicular mycosis fungoides is a type of mycosis fungoides with different clinicopathological and prognostic features.
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